Uncharted 2: Among Thieves, Eurogamer's Game of 2009, has gone on to win a record five statuettes at the Game Developers Conference Awards.
Naughty Dog's sublime PS3 title scooped Game of the Year, Best Writing, Best Technology, Best Visual Arts and Best Audio.
Best Game Design was tipped to be another, but that went to Batman: Arkham Asylum on the night.
DS game Scribblenauts denied Uncharted 2 taking the Innovation Award, and also picked up Best Handheld Game.
Arty PSN game Flower was deemed Best Downloadable Game, and PC action-RPG Torchlight was considered the Best Debut Game.
Facebook's colossus Farmville was awarded Best New Social/Online Game.
The GDC Awards also honoured id Software mastermind John Carmack with a Lifetime Achievement and Gabe Newell with the Pioneer Award for his success at Valve.