Resident Evil 6 launches on PlayStation 3 and Xbox 360 on 20th November 2012, with a PC version to follow later, publisher Capcom has announced.
Set 10 years after the initial Raccoon City outbreak, the game sees series regulars Leon S Kennedy and Chris Redfield dealing with zombie outbreaks across the globe.
As seen in the reveal trailer below, Kennedy is fighting off the undead in a small town in the US after the president gets infected, while Redfield is in an unnamed Chinese metropolis dealing with a bioterrorist threat there.
We reckon we spotted Resident Evil 4 damsel in distress Ashley in there somewhere too.
"From the outset the team's intention was to create an experience that delivers a gripping storyline, tense single-player and co-op action all set against a constant theme of horror. We are calling this fusion dramatic horror and are confident it will resonate with both existing fans of the series as well as newcomers," commented executive producer Hiroyuki Kobayashi
"Resident Evil 6 represents a giant stride forward in the evolution of the series," added Capcom R&D boss Katsuhiko Ichii.
"The development team, led by Hiroyuki Kobayashi, is working tirelessly to deliver the most impressive Resident Evil title ever both in terms of scope and production values. We are all genuinely excited by the title and cannot wait to share it with the world."
That's all the information Capcom has released for now, but promises news on "new characters and co-op details" soon.
The last numbered entry in Capcom's long-running survival horror series came out back in 2009, picking up a 7/10 from Eurogamer. See our Resident Evil 5 review for details.