Nintendo has told Eurogamer there is a "possibility" 3DS games from one region won't work when played by a 3DS from another region.
"Nintendo 3DS hardware is available in three versions: Japanese, American and European/Australian. Nintendo has developed different versions of Nintendo 3DS hardware to take into account different languages, age rating requirements and parental control functionality, as well as to ensure compliance with local laws in each region," a Nintendo statement explained.
"Nintendo 3DS also offers network services specifically tailored for each region.
"Additionally we want to ensure the best possible gaming experience for our users, and There is the possibility that Nintendo 3DS software sold in one region will not function properly when running on Nintendo 3DS hardware sold in another."
The statement added: "Guidance will appear on every packaging of Nintendo 3DS hardware and the accompanying software. If you are in doubt, Nintendo recommends that you only purchase Nintendo 3DS software in the region where purchased your Nintendo 3DS system."
Reports that the 3DS was region-locked spilled earlier this month. Let's hope Nintendo can bring Japanese and Western releases closer to compensate.