The Nintendo DS handheld has shipped over 100 million units worldwide as of 6th March 2009, GamesIndustry.biz reports.
The milestone comes ahead of the release of the latest in the series, the DSi, due in Europe and the US on 3rd April.
As of December, there are 83 DS titles which have shipped over one million units each, seven of those shipping upwards of 10 million copies.
The original DS launched in early 2005 in Europe, followed by the slimmer DS Lite. The DSi features two cameras, and the ability to record, manipulate and play sound files.
Check out Eurogamer's thoughts on the DSi launch elsewhere on the site.