Take a look at Nuclear Throne, the latest from Vlambeer
It's a roguelike with lots of guns in it.
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Nuclear Throne is Vlambeer's latest chunk of glorious blasty chaos - a roguelike set in a mutated wasteland where you scrabble around for guns, shoot anything that slithers towards you, and occasionally grow another appendage or two when you level up. The game's currently available through Steam's Early Access service, and although it's clearly got a long way to go, it's already an insane amount of fun.
I've been playing a little bit of it this morning, and trying to record some of what happened. Also, I've been attempting to talk over the top of the whole thing while playing. It wasn't the greatest success story in the world. Have a look!