Well, I'd imagine they would redesign it that way for browsing media functions (internet, netflix etc). Though there have been some extremely popular RTS games recently. If it would allow for a console Starcraft 2 and Total War game I'm sure they would do well.
Though no, I don't seriously think it would ever happen. It would be easier just to slap a touch screen on there. Also mouse control would probably undermine any motion control ideas they are likely going to build into the thing.