I have the same setup and it runs smoooooth. Don't even notice framerate drops when it all goes tits up.
I'm running a core i5 750 @ 3.6 overclock, 8 gig 1600mhz RAM and a GTX 570 1.3gig. Game runs at 1900x1200 @60fps with most stuff on high when there's not much going on, drops to around 30 when there's big fights happening.
I'm building a gaming rig for this...Looks amazing. Does it require a very powerful machine to run?
I reckon you'd want at least a core i5 2500k, seems more CPU bound than GPU at the moment.