EA has announced Dead Space 2 for PC, PS3 and Xbox 360, but hasn't said when it's due out or whether it includes multiplayer.
All we know of the sequel is that Visceral Games will once more develop and hero Isaac Clarke will return. This time, however, he'll have new tools to "slice and dismember" with as he takes the fight to the Necromorph menace. He's gone all Sigourney Weaver, it sounds like.
Dead Space was a third-person survival-horror game that followed mechanic Isaac Clarke as he chased down a distress call made by the spaceship Ishimura. Turns out there were nasty aliens on board.
The atmospheric PC, PS3 and Xbox 360 game quickly gathered a strong following, although we ended up giving it 7/10 at the time.