YouTube user digitalarts001 has used PlayStation Mobile to power PC and Xbox 360 game Left 4 Dead on Vita.
The video, below, shows Valve's zombie shooter running on the handheld, complete with motion input to move the camera.
It looks like digitalarts001 has written an app for Vita, using PlayStation Mobile, that connects to a remote version of Windows and plays Left 4 Dead on Steam over a local network with little lag.
digitalarts001 has published a number of videos of games running on Vita, including Super Mario Bros. 3, Final Fantasy 10 and Metal Gear Solid.
PlayStation Mobile is what used to be called PlayStation Suite, Sony's program to create a range of PlayStation-certified content available on devices that meet the PlayStation Certified requirements (right now, this means devices that run Android, and Vita). It's currently in open beta.
More than 50 developers are creating content for PlayStation Mobile, with the SDK freely available to software houses under the PlayStation Mobile Developer Program.
Last month Sony Europe boss Jim Ryan said PlayStation Mobile will avoid the usual app store "junk".
"[We're] ensuring that anything that is offered on this platform is of proper PlayStation quality," he said.
"People [will] feel comfortable and safe that they are not going to inadvertently stumble upon any of the junk that exists in that wider marketplace.
He added: "It's a significant business challenge because it's our brand that's at risk here and it's our responsibility as a platform holder in multiple directions to ensure we do that. Can we be completely laissez faire? I don't think so because then we'll end up just like all the rest and that can't happen."