Cammie Dunaway is leaving her role as head of marketing for Nintendo of America.
The executive is known for her appearances at Nintendo's press conferences at E3 2008 and E3 2009, and her ability to carry off white trouser suits.
Dunaway will leave the company on 1st October for unspecified reasons.
"I'm thankful for my time with Nintendo and proud of our team's accomplishments in growing the Nintendo audience," she said in a statement. "I look forward to watching the continued growth of the Nintendo brand in the years ahead."
NOA boss Reggie Fils-Aime added, "We appreciate Cammie's contributions to Nintendo and the role she played in bringing the Wii and Nintendo DS experiences to millions of people."